![]() Pneumatic actuation assembly
专利摘要:
PNEUMATIC ACTUATION ASSEMBLY Abstract An actuator assembly (200) is provided. The actuator assembly (200) includes housing (202) configured for operable engagement by a user, a trigger assembly (204) operably supported on the housing (202), a gas cartridge (210) releasably secured to the housing (202), a valve assembly (220) mounted within the housing (202) for controlling the flow of pressurized gas through the housing (202) and a cylinder actuator (225) operably operably connected to the valve assembly (220). The cylinder actuator (225) includes a piston (328) selectively extendable therefrom configured for depressing a plunger (62). The piston (328) includes a head (328a) having an inlet surface (128a) disposed within an inlet chamber (327a) of the cylinder actuator (225) and an outlet surface (128b) disposed within the outlet chamber (327b) of the cylinder actuator (225). The exposed surface area of the first surface is equal to the exposed surface of the second surface. 329b 327b 325b 325a 32a 328b 329328a F] G. 9 公开号:AU2013207580A1 申请号:U2013207580 申请日:2013-07-17 公开日:2014-02-27 发明作者:Les Hull 申请人:Confluent Surgical Inc; IPC主号:A61M5-145
专利说明:
1 PNEUMATIC ACTUATION ASSEMBLY Cross-Reference to Related Applications [0001] This application claims the benefit of and priority to U.S. Patent Application Nos. 61/681,706, filed August 10, 2012, and 13/922,640, filed June 20, 2013, the entire disclosure of which is incorporated by reference herein. Field [0002] The present disclosure relates to applicator assemblies for mixing and dispensing components. More particularly, the present disclosure relates to pneumatic actuator assemblies for controlling the flow of the components through and from the applicator assembly. Background [0003] Applicator assemblies for mixing and dispensing components are known. Many of these applicator assemblies include component filled syringes for supplying the components to a mixing assembly. One such applicator assembly is disclosed in commonly own U.S. Patent No. 8,033,483, the content of which is incorporated herein by reference in its entirety. In use, a clinician manually depresses the plungers of the syringes to supply the components to the mixing assembly. When the syringes are manually actuated, the rate at which the mixed components flow through and from the applicator assembly tends to vary. Since many mixing assemblies require a specific rate to operate effectively, the inconsistent flow rate can be problematic. [0004] To provide a more consistent flow of components through the applicator and to a surgical site, a surgeon may attach the applicator assembly to a powered actuator assembly configured for depressing the plungers of the syringes in a consistent and controlled manner. Some of these actuator assemblies are pneumatically-powered, such that when the assembly is actuated, e.g., a trigger is squeezed, compressed fluid, typically air from a gas cartridge, is supplied to a 2 pneumatic cylinder actuator to cause a piston within the actuator to advance, thereby depressing the plungers of syringes in a consistent and controlled manner. [0005] Although pneumatically powered actuator assemblies are known, these assemblies experience a phenomenon known as "coasting." As will be discussed in greater detail below, the result of coasting is a continued flow of material from the applicator assembly after the actuator assembly has been deactivated, i.e., upon release of the trigger. Coasting may result in gooping, dribbling or other unwanted flow of the mixed components. As will also be discussed in greater detail below, coasting also prevents defined stops or boundaries when applying the mixed components. [0006] Therefore, it would be beneficial to have an actuator assembly in which coasting is greatly reduced or eliminated altogether. Object [0007] It is the object of the present invention to substantially overcome or ameliorate one or more of the disadvantages of the prior art, or at least provide a useful alternative. Summary [0008] Accordingly, an actuator assembly is provided. The actuator assembly includes a housing configured for operable engagement by a user, a trigger assembly operably supported on the housing, a gas cartridge releasably secured to the housing, a valve housing mounted within the housing for controlling the flow of pressurized gas through the housing, and a cylinder actuator including a piston selectively extendable therefrom configured for depressing a plunger. The piston includes a head having an inlet surface disposed within an inlet chamber of the cylinder actuator and an outlet surface disposed within the outlet chamber of the cylinder actuator. The exposed surface area of the first surface is equal to the exposed surface of the second surface. 3 [0009] In some embodiments, the piston includes a first shaft extending from the inlet surface of the head and a second shaft extending from the outlet surface of the head. The piston may include a shaft extending through the head such that the shaft extends from both the inlet and outlet surfaces of the head. Alternatively, the cylinder actuator includes first and second sections and the piston includes a first head disposed within the first section and a second head disposed within the second section. A first shaft extends between the first and second heads and second shaft extends from the second head, wherein an exposed surface area of the first head is equal to an exposed surface area of the second head. The housing may be configured for operable connection with an applicator assembly. The valve housing may include at least a first actuator valve and at least a first dispense on/off valve. The valve housing may further include at least one solenoid valve. In some embodiments, the housing includes a pencil grip. Alternatively, the housing may include a pistol grip. [0010] Also provided is a system including an applicator assembly and an actuator assembly. The applicator assembly includes at least one syringe having a plunger. The actuator assembly is configured for operable connection to the applicator assembly. The actuator assembly includes a cylinder actuator including a piston selectively extendable therefrom for depressing the plunger. The piston includes a head having an inlet surface disposed within an inlet chamber of the cylinder actuator and an outlet surface disposed within the outlet chamber of the cylinder actuator. The exposed surface area of the first surface and the second surface are equal. Brief Description of Drawings [0011] The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments of the disclosure and, together with a general description of the disclosure given above, and the detailed description of the embodiments given below, serve to explain the principles of the disclosure, wherein: [0012] FIG. 1 is a schematic diagram of an embodiment of an actuator assembly according to the present disclosure; 4 [0013] FIG. 2 is a graph showing the flow rate of mixed components exiting an applicator assembly that is actuated by the actuator assembly schematically illustrated in of FIG. 1; [0014] FIG. 3 is top view of a splatter sheet resulting from the flow of mixed components from the applicator assembly illustrated in the graph of FIG. 2; [0015] FIG. 4 is a schematic diagram of an actuator assembly according to another embodiment of the present disclosure; [0016] FIG. 5 is a graph showing the flow rate of mixed components exiting an applicator assembly that is actuated by the actuator assembly schematically illustrated in FIG. 4; [0017] FIG. 6 is a top view of a splatter sheet resulting from the flow of mixed components from the applicator assembly illustrated in the graph of FIG. 5; [0018] FIG. 7 is a side view an actuator assembly according to another embodiment of the present disclosure schematically illustrating the components therein and including an applicator assembly operably attached thereto; [0019] FIG. 8 is side view of an actuator assembly according to yet another embodiment of the present disclosure schematically illustrating the components therein and including an applicator assembly operably attached thereto; and [0020] FIG. 9 is a schematic diagram of a cylinder actuator according to an embodiment of the present disclosure. Description of Embodiments [0021] Embodiments of the presently disclosed applicator assembly will now be described in detail with reference to the drawings in which like reference numerals designate identical or corresponding elements in each of the several views. 5 [0022] As discussed above, prior art pneumatically-powered actuator assemblies for use with applicator assemblies experience a phenomenon known as coasting. As will be discussed in further detail below, it has been determined that coasting occurs as a result of the reduced stopping force caused by the configuration of the piston head of the cylinder actuator. [0023] With reference to FIG. 1, a schematic diagram of a pneumatic actuator assembly according to a first embodiment of the present disclosure is shown generally as actuator assembly 1. Actuator assembly 1 includes a gas supply 10, a primary actuator charge valve 15, a secondary actuator charge valve 20, a single-ended actuator cylinder 25, a dispense on/off valve 30, an accumulator 35 and a solenoid valve 40. Single-ended actuator cylinder 25 is configured to depress a plunger 62 (FIG. 7) of an applicator assembly 50 (FIG. 7). Actuator cylinder 25 includes a piston 26 having a head 28 and a shaft 29. Actuator cylinder 25 defines a cavity 27. Head 28 of piston 26 divides cavity 27 of actuator cylinder 25 into an inlet chamber 27a and an outlet chamber 27b. Inlet chamber 27a includes an inlet 27c and outlet chamber 27b includes an outlet 27d. Head 28 of piston 26 includes an inlet surface 28a disposed within inlet chamber 27a and an outlet surface 28b disposed within outlet chamber 27b. [0024] The operation of actuator assembly 1 will now be described with reference to FIG. 1. Prior to use, gas supply 10 is loaded into actuator assembly 1, if not already done so, and gas supply 10 is opened, i.e., a seal is punctured. Actuator cylinder 25 is then charged by opening primary actuator charge valve 15. Once actuator cylinder 25 is fully charged, primary actuator charge valve 15 is closed. Secondary actuator charge valve 20 remains open after charging. When fully charged, the pressure within each of inlet and outlet chambers 27a, 27b of actuator cylinder 25 are equal, as are the forces acting on head 28 of piston 26, therefore piston 26 is stationary. [0025] To actuate single-ended actuator cylinder 25, dispense on/off valve 30 is opened, i.e., a trigger is squeezed. Opening of dispense on/off valve 30 permits pressurized gas to flow from outlet 27d in outlet chamber 27b of actuator cylinder 25 and pressurized gas to flow through inlet 27c of inlet chamber 27a of actuator cylinder 25 into inlet chamber 27a. As the pressurized air flows from outlet chamber 27b and into inlet chamber 27a, the difference in pressure acting on head 28 of piston 26 causes piston 26 to advance distally, in the direction of arrow "A". Once dispense 6 on/off valve 30 is closed, pressurized gas no longer flows from outlet chamber 27b through outlet 27d, and the pressure within outlet chamber 27b and the pressure within inlet chamber 27a equalize to prevent further advancement of piston 26. In this manner, piston 26 no longer depresses plunger 62 (FIG. 7) of applicator assembly 50 (FIG. 7), thereby stopping the flow of mixed components from the applicator assembly. [0026] With reference to the graph of FIG. 2, tests were conducted to measure the rate of the mixed components flowing from an applicator assembly while using actuator assembly 1. During the test, actuator assembly 1 was actuated (started and stopped) four times (A, B, C, D). As seen in the graph of FIG. 2, the start of each actuation is represented by a substantially vertical line, which represents the nearly instantaneous flow of mixed components from the applicator assembly upon actuation of actuator assembly 1. First actuation (A) was stopped at a time T 1 , second actuation (B) was stopped at a time T 2 , third actuation (C) was stopped at a time T 3 , and fourth actuation (D) was stopped at a time T 4 . As can be seen in the graph, the time at which the mixed components ceased flowing, i.e., attained a flow rate of zero (0), lags from the time each actuation was stopped. The amount of mixed component that is dispensed after actuator assembly 1 is stopped is indicated by the shaded areas of the graph and is a result of the coasting that occurs within single-ended actuator cylinder 25. [0027] A spray sheet created during the testing of actuator assembly 1 is shown in FIG. 3. As can be seen, there is no distinct boundary at the stop of each actuation. Instead, after each stoppage, mixed component continued to flow from the applicator assembly. As discussed above, this overflow may result in gooping and/or dribbling of the mixed component, thereby increasing the difficulty of performing a clean application of the mixed components. [0028] Following testing, it was determined that the coasting in actuator assembly 1 occurs as a result of the reduced stopping force provided by outlet surface 28b of piston head 28. Specifically, the exposed surface area of outlet surface 28b, i.e., the area of piston head 28 disposed within outlet cavity 28b, is less than the exposed surface area of inlet surface 28a, i.e., the area of piston head 28 disposed within inlet cavity 28a. As seen in FIG. 1, the difference in exposed surface areas is caused by the surface area of distal surface 28b that is covered by shaft 29. The difference in 7 exposed surface area of inlet and outlet surfaces 28a, 28b of head 28 of piston 26 results in there being less stopping force against outlet surface 28b subsequent to the closing of dispense on/off valve 30. The time it takes for forces acting on inlet surface 28a and outlet surface 28b of piston head 28 to equalize is the lag time, or length of time mixed components continue to flow from the applicator assembly. [0029] Further testing found that by increasing the size of piston head 28 in relation to the diameter of shaft 29, the effect of coasting could be greatly reduced. It was also determined that although included, there was not a need for accumulator 35 on the first actuation of actuator assembly 1, as applicator assembly 50 (FIG. 7) had not yet been used, and actuator assembly 1 could operate effectively without accumulator 35 in the subsequent actuations despite the any obstructions caused by previous use. In use, accumulator 35 provides actuator assembly 1 with an initial burst of speed during actuation. [0030] With reference now to FIG. 4, a schematic of an actuator assembly according to another embodiment of the present disclosure is shown generally as actuator assembly 100. Actuator assembly 100 includes a gas supply 110, a primary actuator charge valve 115, a secondary actuator charge valve 120, a double-ended actuator cylinder 125, a first solenoid valve 130 and a dispense on/off valve 135, and may optionally include an accumulator 40, an accumulator on/off valve 45 and a solenoid valve 50. Actuator assembly 100 is substantially similar to actuator assembly 1 and, therefore, will only be described as relates to the difference therebetween. Actuator assembly 100 includes a doubled-ended actuator cylinder 125 having a piston 126 including a head 128, a first shaft 129a extending from an inlet surface 128a of head 128 and a second shaft 129b extending from an outlet surface 128b of head 128. [0031] During operation of actuator assembly 100, i.e., opening of dispense on/off valve 135, piston 126 is moved distally within cavity 127 of actuator cylinder 125 due to the flow of pressurized gas into inlet chamber 127a and out of outlet chamber 127b. Upon closing of dispense on/off valve 135, the flow of pressurized gas into inlet chamber 127a and out of outlet chamber 127b is stopped. Because each of inlet and outlet surfaces 128a, 128b of head 128 include shaft 129a, 129b, respectively, extending therefrom, the exposed surface areas of each of inlet and outlet 8 surfaces 128a, 128b of head 128 are the same. As a result, the stopping force of outlet surface 128b is equal to the driving force against inlet surface 128a, thereby ceasing the advancement of piston head 128 immediately or almost immediately upon closing of dispense on/off valve 135. The equalization of the pressure within inlet and outlet chambers 127a, 127b may be further facilitated by solenoid valve 130 which is disposed between inlet 127c and outlet 127d of cylinder actuator 100 and is opened as dispense on/off valve 135 is closed. [0032] With reference to the graph in FIG. 5, tests similar to those discussed above with regards to actuator assembly 1 were conducted to measure the rate of the mixed components flowing from a similar applicator assembly while using actuator assembly 100. During the tests, actuator assembly 100 was actuated (started and stopped) five times (A', B', C', D', E'). Similar to the graph of FIG. 2, the start of each actuation is represented by a substantially vertical line which represents the nearly instantaneous flow of mixed components from the applicator assembly upon actuation of actuator assembly 100. First actuation (A') was stopped at a time T 1 ', second actuation (B') was stopped at a time T 2 ', third actuation (C') was stopped at a time T 3 ', fourth actuation (D') was stopped at a time T 4 ', and fifth actuation (E') was stopped at a time T5'. As can be seen in the graph, the time at which the mixed components ceased flowing, i.e., attained a flow rate of zero (0), occurs almost immediately upon deactivation of actuation assembly 100. The amount of mixed component that is dispensed after actuator assembly 100, as indicated by the area between the stop time and the line representing the flow rate, is nominal. [0033] As with the previous test, a spray sheet was created during the testing of actuator assembly 100. As seen in the spray sheet shown in FIG. 6, there is a clear and distinct boundary at the stop of each actuation. As discussed above, the immediate or nearly immediate response achieved when using actuating the applicator assembly using actuation assembly 100 allows for a cleaner and more consistent application of mixed components. [0034] As seen in the graph of FIG. 5, the flow rate of the first actuation is greater than the flow rate of the subsequent actuations. This is a result of applicator assembly 50 being unused, and therefore without any obstruction. As noted above, while included, testing showed that accumulator 135 was not necessary to the effective operation of actuator assembly 100. 9 [0035] With reference to FIG. 7, an embodiment of an actuator assembly according to the aspects of the present disclosure is shown generally as actuator assembly 200. Actuator assembly 200 includes a housing 202, a trigger assembly 204, a gas cartridge 210, a valve housing 220 and a double-ended cylinder actuator 225. As shown, housing 202 and trigger assembly 204 are in the form of a pistol grip. Although not shown, valve housing 220 includes one or more valves, i.e., solenoid, charge, dispense on/off, as discussed above for controlling the flow of pressurized gas through cylinder actuator 225. Housing 202 of actuator assembly 200 is configured to operably receive an applicator assembly 50. Applicator assembly 50 includes a source of components, i.e., syringes 60, a manifold 70, an elongated body 80 and a mixing/dispensing tip 90. Plunger 62 of syringes 60 are disposed adjacent to distal end of outlet shaft 229b of piston (not shown) of double ended actuator 225. Syringes 60 and cylinder actuator 225 are arranged such that distal advancement of shaft 229b causes depression of plunger 62. Although the aspects of the present disclosure are being described for use with applicator assembly 50, it is envisioned that the aspects of the present disclosure may be modified for use with other applicator assemblies. [0036] As discussed above, because actuator assembly 200 utilizes a doubled ended cylinder actuator 225, the surface areas of inlet and outlet surfaces (not shown) of head (not shown) of piston (not shown) are equal, therefore the equalization in pressure of inlet and outlet chambers (not shown) is nearly immediate. Thus, any coasting that was previously experienced as a result of differing exposed surface areas of the piston head is eliminated in actuator assembly 200, as the exposed surface areas of the piston head in double-ended cylinder actuator 225 are the same. Actuator assembly 200 may also include a solenoid (not shown) disposed between the inlet and the outlet to further assist in the immediate equalization of the pressure in the inlet chamber and the outlet chamber. [0037] Turning to FIG. 8, another embodiment of an actuator assembly according to the present disclosure is shown generally as actuator assembly 300. Actuator assembly 300 is substantially similar to actuator assembly 200 in form and function. Actuator assembly 300 includes a housing 302 and a trigger assembly 304 in the form of a pencil grip. Actuator assembly 300 further includes a gas cartridge 310, a valve housing 320 and a double-ended cylinder actuator 325. Applicator assembly 50 is operably connected to housing 302 of actuator assembly 300. 10 [0038] Either or both of actuator assemblies 200, 300 may include indicators (not shown) for indicating the amount of pressurized gas remaining in respective gas cartridges 210, 310, the amount of component remaining in respective syringes 60, the flow rate of the components from applicator assembly 50, and/or any other various conditions that may be monitored during the use of actuator assemblies 200, 300. [0039] As discussed above, the coasting within actuator assembly 1 was caused by the difference in surface area between the inlet surface and the outlet surface of the head of the piston. As also discussed above, one solution to this problem was addressed by adding a shaft to the inlet surface of the piston head such that each of the inlet and outlet surfaces of the head includes shaft 129a (FIG. 4). Shaft 129a functions solely as a space holder to make equal the exposed surface areas of inlet surface 128a and outlet surface 128b of piston head 128. [0040] With reference to FIG. 9, an alternative means of equalizing the exposed surface areas of inlet and outlet surface of a piston head is shown. Cylinder actuator 325 includes a first section 325a defining an inlet chamber 327a and a second section 325b defining an outlet chamber 327b. A piston 328 includes a first piston head 328a received within inlet chamber 327a and a second piston head 328b received within outlet chamber 327b. First and second piston heads 328a, 328b are connected by a shaft 329. Shaft 329 may extend through second piston head 328b, or instead a second shaft may extend distally from second piston head 328b. Inlet and outlet chambers 327a, 327b and first and second piston head 328a, 328b are sized such that the surface area on the inlet side of first piston head 328a is equal to the exposed surface area on the outlet side of second piston head 328b, i.e., the surface area of second piston head 328b minus the surface are covered by shaft 329. In this manner, the coasting experienced in applicator assembly 50 as a result of cylinder actuator 325 during use of an actuator assembly including cylinder actuator 325 is eliminated or nearly eliminated. 11 [0041] Although the illustrative embodiments of the present disclosure have been described herein with reference to the accompanying drawings, it is to be understood that the disclosure is not limited to those precise embodiments, and that various other changes and modifications may be effected therein by one skilled in the art without departing from the scope or spirit of the disclosure.
权利要求:
Claims (10) [1] 1. An actuator assembly comprising: housing configured for operable engagement by a user; a trigger assembly operably supported on the housing; a gas cartridge releasably secured to the housing; a valve housing mounted within the housing for controlling the flow of pressurized gas through the housing; and a cylinder actuator including a piston selectively extendable therefrom configured for depressing a plunger, the piston including a head having an inlet surface disposed within an inlet chamber of the cylinder actuator and an outlet surface disposed within the outlet chamber of the cylinder actuator, wherein the exposed surface area of the first surface is equal to the exposed surface of the second surface. [2] 2. The actuator assembly of claim 1, wherein the piston includes a first shaft extending from the inlet surface of the head and a second shaft extending from the outlet surface of the head. [3] 3. The actuator assembly of claim 1, wherein the piston includes a shaft extending through the head such that the shaft extends from both the inlet and outlet surfaces of the head. [4] 4. The actuator assembly of claim 1, wherein the cylinder actuator includes first and second sections and the piston includes a first head disposed within the first section and a second head disposed within the second section, a first shaft extends between the first and second heads and second shaft extends from the second head, wherein an exposed surface area of the first head is equal to an exposed surface area of the second head. [5] 5. The actuator assembly of claim 1, wherein the housing is configured for operable connection with an applicator assembly. [6] 6. The actuator assembly of claim 1, wherein the valve housing includes at least a first actuator valve and at least a first dispense on/off valve. [7] 7. The actuator assembly of claim 6, wherein the valve housing further includes at least one solenoid valve. 13 [8] 8. The actuator assembly of claim 1, wherein the housing includes a pencil grip. [9] 9. The actuator assembly of claim 1, wherein the housing includes a pistol grip. [10] 10. A system comprising: an applicator assembly including at least a first syringe, wherein the at least first syringe includes plunger; and an actuator assembly operably connected to the applicator assembly, wherein the actuator assembly includes a cylinder actuator including a piston selectively extendable therefrom for depressing the plunger, the piston including a head having an inlet surface disposed within an inlet chamber of the cylinder actuator and an outlet surface disposed within the outlet chamber of the cylinder actuator, wherein the exposed surface area of the first surface and the second surface are equal. Confluent Surgical, Inc. Patent Attorneys for the Applicant/Nominated Person SPRUSON & FERGUSON
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同族专利:
公开号 | 公开日 AU2013207580B2|2017-02-16| AU2013207580C1|2017-05-25| EP2695595A2|2014-02-12| EP2695595A3|2015-06-03| CA2821459A1|2014-02-10| EP2695595B1|2019-11-06| US20140041375A1|2014-02-13| US10309430B2|2019-06-04| CA2821459C|2020-03-31|
引用文献:
公开号 | 申请日 | 公开日 | 申请人 | 专利标题 US1210179A|1915-10-18|1916-12-26|William H Lewis|Grease-gun.| US3214102A|1963-09-23|1965-10-26|Meyer Geo J Mfg Co|Self-cleaning nozzles| US3768472A|1972-02-07|1973-10-30|M Hodosh|Fluid dispensing gun| US3828980A|1972-11-06|1974-08-13|Chem Dev Corp|Dispenser for precisely metered dispensing of viscous fluids| US3980209A|1973-12-10|1976-09-14|Roean Industries|Bulk loading plastic compound dispensing device| US4040420A|1976-04-22|1977-08-09|General Dynamics|Packaging and dispensing kit| AT366916B|1980-04-02|1982-05-25|Immuno Ag|DEVICE FOR APPLICATING A TISSUE ADHESIVE BASED ON HUMAN OR ANIMAL PROTEINS| US4538920A|1983-03-03|1985-09-03|Minnesota Mining And Manufacturing Company|Static mixing device| AT379311B|1984-03-29|1985-12-27|Immuno Ag|DEVICE FOR APPLICATING A TISSUE ADHESIVE| US4634027A|1985-01-04|1987-01-06|Mvm Valve Co., Inc.|Liquid dispensing apparatus and an anti-drip valve cartridge therefor| AT382783B|1985-06-20|1987-04-10|Immuno Ag|DEVICE FOR APPLICATING A TISSUE ADHESIVE| US4767416A|1986-12-01|1988-08-30|Johnson & Johnson Patient Care, Inc.|Spray nozzle for syringe| US4767026A|1987-01-16|1988-08-30|Keller Wilhelm A|Dispensing and mixing apparatus| USRE36235E|1987-01-16|1999-06-29|Wilhelm Keller|Dispensing and mixing apparatus| US4753536A|1987-03-09|1988-06-28|Spehar Edward R|Dispensing mixer for the storage and mixing of separate materials| US4842581A|1987-09-11|1989-06-27|Davis Richard C|Medical lavage apparatus| US4978336A|1987-09-29|1990-12-18|Hemaedics, Inc.|Biological syringe system| US5116315A|1989-10-03|1992-05-26|Hemaedics, Inc.|Biological syringe system| US4872368A|1988-07-28|1989-10-10|Orscheln Co.|Push-to-release cable operating apparatus| US5226877A|1989-06-23|1993-07-13|Epstein Gordon H|Method and apparatus for preparing fibrinogen adhesive from whole blood| US4979942A|1989-10-16|1990-12-25|Johnson & Johnson Medical, Inc.|Two component syringe delivery system| US5104375A|1989-10-16|1992-04-14|Johnson & Johnson Medical, Inc.|Locking holder for a pair of syringes and method of use| US5249709A|1989-10-16|1993-10-05|Plas-Pak Industries, Inc.|Cartridge system for dispensing predetermined ratios of semi-liquid materials| US5049135A|1990-09-18|1991-09-17|Code Blue Medical Corporation|Medical lavage apparatus| DE9017323U1|1990-12-21|1992-04-16|Thera Patent Gmbh & Co Kg Gesellschaft Fuer Industrielle Schutzrechte, 8031 Seefeld, De|| US5383851A|1992-07-24|1995-01-24|Bioject Inc.|Needleless hypodermic injection device| US5333760A|1992-12-28|1994-08-02|Coltene/Whaledent, Inc.|Dispensing and mixing apparatus| US5328462A|1993-09-03|1994-07-12|Ultradent Products, Inc.|Methods and apparatus for mixing and dispensing multi-part compositions| US5665066A|1993-09-03|1997-09-09|Ultradent Products, Inc.|Methods and apparatus for mixing and dispensing multi-part compositions| US5445614A|1993-10-20|1995-08-29|Habley Medical Technology Corporation|Pharmaceutical storage and mixing syringe| US5413253A|1993-12-06|1995-05-09|Coltene/Whaledent, Inc.|Static mixer| US5474540A|1994-03-25|1995-12-12|Micromedics, Inc.|Fluid separation control attachment for physiologic glue applicator| AT206078T|1994-06-28|2001-10-15|Aventis Behring Gmbh|DEVICE FOR SPRAYING A MIXTURE OF TWO COMPONENTS| US5810885A|1994-12-28|1998-09-22|Omrix Biopharm Sa|Device for applying one or several fluids| US6835186B1|1995-01-16|2004-12-28|Baxter International, Inc.|Mechanical breakup unit for biochemically reactive fluid delivery device| US5918772A|1995-03-13|1999-07-06|Wilhelm A. Keller|Bayonet fastening device for the attachment of an accessory to a multiple component cartridge or dispensing device| US6769574B1|1995-03-13|2004-08-03|Mixpac Systems Ag|Dispensing assembly having coded attachment of an accessory to a multiple component cartridge or dispensing device using differently sized inlets and outlets| US5542336A|1995-04-17|1996-08-06|Martin Marietta Corporation|Positioning apparatus and method utilizing PWM control of a double-acting hydraulic cylinder| EP0738498A1|1995-04-18|1996-10-23|Machida Endoscope Co., Ltd|Surgical adhesive sprayer| IL127619D0|1996-07-01|1999-10-28|Pharmacia & Upjohn Ab|Delivery device and method for its operation| DE19643343A1|1996-10-21|1998-04-23|Bosch Gmbh Robert|Slip-controlled hydraulic vehicle brake system| US5890655A|1997-01-06|1999-04-06|The Procter & Gamble Company|Fan spray nozzles having elastomeric dome-shaped tips| US6783514B2|1997-01-31|2004-08-31|United States Surgical Corporation|Fibrin sealant applicator| US6994686B2|1998-08-26|2006-02-07|Neomend, Inc.|Systems for applying cross-linked mechanical barriers| US5941462A|1997-03-25|1999-08-24|John R. Woods|Variable spray nozzle for product sprayer| US5819988A|1997-04-01|1998-10-13|Sawhney; Ravi K.|Double-barreled syringe with detachable locking mixing tip| US6065645A|1997-04-01|2000-05-23|Discus Dental Impressions, Inc.|Double-barreled syringe with detachable locking mixing tip| US6458095B1|1997-10-22|2002-10-01|3M Innovative Properties Company|Dispenser for an adhesive tissue sealant having a housing with multiple cavities| US7128278B2|1997-10-24|2006-10-31|Microdiffusion, Inc.|System and method for irritating with aerated water| ES2346679T3|1997-12-19|2010-10-19|Tyco Healthcare Group Lp|TWO COMPONENT DISPENSING SYSTEM.| US6047861A|1998-04-15|2000-04-11|Vir Engineering, Inc.|Two component fluid dispenser| US6475183B1|1998-06-03|2002-11-05|Baxter International Inc.|Direct dual filling device for sealing agents| JP2000126569A|1998-09-18|2000-05-09|Sulzer Chemtech Ag|Device for mixing and distributing a plurality of flowing components| US6394314B1|1999-10-12|2002-05-28|Discus Dental Impressions, Inc.|Double-barreled syringe with detachable locking mixing tip| US6328229B1|1998-12-18|2001-12-11|Cohesion Technologies, Inc.|Low volume mixing spray head for mixing and dispensing of two reactive fluid components| US6756069B2|1999-05-18|2004-06-29|Nestec S.A.|System and method for dispensing a liquid beverage concentrate| US6365080B1|1999-06-09|2002-04-02|Ronald J. Parise|Method of making a multi-portion mixing element| FR2796925B1|1999-07-29|2001-10-05|Valois Sa|DISPENSER WITH ARTICULATED DISPENSING HEAD| AT289499T|2000-01-18|2005-03-15|Zimmer Gmbh|PISTOL FOR EXPRESSING BONE CEMENT WITH AN APPLICABLE COMPOSITE SPRAY| AU784250B2|2000-03-16|2006-03-02|Covidien Lp|Declogging multilumen discharge assembly| AU8059501A|2000-07-17|2002-01-30|Haemacure Corp|Spray head for applying a multi-component mixture| US20020165483A1|2000-11-10|2002-11-07|Curtis Miller|Gas assisted spray applicator| DE10060513A1|2000-12-06|2002-06-20|Illbruck Gmbh|Cartridge kit, useful for generating polyurethane building foams, includes expandable graphite as a fire protection additive| US6585696B2|2000-12-22|2003-07-01|Baxter International, Inc.|Method and apparatus for applying a medically useful multiple component material| SE0100091D0|2001-01-12|2001-01-12|Pharmacia Ab|A device and a method for dispensing at least two mutually reactive components| US6398761B1|2001-01-19|2002-06-04|Ultradent Products, Inc.|Double syringe barrels with ported delivery ends| US7267288B2|2001-03-22|2007-09-11|Nevada Supply Corporation|Polyurethane in intimate contact with fibrous material| US6915964B2|2001-04-24|2005-07-12|Innovative Technology, Inc.|System and process for solid-state deposition and consolidation of high velocity powder particles using thermal plastic deformation| US6663596B2|2001-08-13|2003-12-16|Scimed Life Systems, Inc.|Delivering material to a patient| GB0121377D0|2001-09-04|2001-10-24|Aqualisa Products Ltd|Shower handset| FI20011787A|2001-09-10|2003-03-11|Marioff Corp Oy|Method at the spray head and at the spray head| US6921381B2|2001-10-05|2005-07-26|Baxter International Inc.|Laparoscopic spray device and method of use| FR2830778B1|2001-10-11|2004-07-09|Oreal|DEVICE FOR SPRAYING AT LEAST ONE PRODUCT ON A SUPPORT, IN PARTICULAR A KERATINIC SUPPORT SUCH AS THE SKIN| US6921680B2|2001-12-31|2005-07-26|Texas Instruments Incorporated|Method and apparatus for MEMS device nebulizer lubrication system| US6732887B2|2002-03-26|2004-05-11|Ultradent Products, Inc.|Two-part composition syringe delivery system| US6852099B2|2002-06-04|2005-02-08|Baxter International Inc.|Device for controllably applying liquids to body surfaces| US6609666B1|2002-07-24|2003-08-26|William Sydney Blake|Unitary over-mold non-clog system with positive shutoff| ES2313288T3|2004-02-13|2009-03-01|HENKEL AG & CO. KGAA|DISPENSING BOTTLE FOR AT LEAST TWO ACTIVE FLUIDS.| US7217254B2|2002-09-20|2007-05-15|Genzyme Corporation|Multi-pressure biocompatible agent delivery device and method| ITMO20020321A1|2002-11-06|2004-05-07|Sidam Di Azzolini Graziano E C S A S|GROUP FOR THE MIXING OF INSERIBLE FLUIDS ALONG LINES| US7173733B2|2002-11-07|2007-02-06|University Of Delaware|Method for modeling color halftones| US7124574B2|2002-12-04|2006-10-24|United Technologies Corporation|Method and apparatus for a substantially coaxial injector element| FR2848998B1|2002-12-20|2006-04-07|Oreal|DISPENSING DEVICE HAVING MEANS FOR DISTRIBUTING TWO PRODUCTS IN VARIABLE PROPORTIONS| DK1497034T3|2002-12-20|2006-11-13|Lifecycle Pharma As|A self-cleaning spray nozzle| US7124914B2|2003-01-08|2006-10-24|Continentalafa Dispensing Company|Dual chamber lotion pump| US7140558B2|2003-03-24|2006-11-28|Irene Base, legal representative|Mixing arrangement for atomizing nozzle in multi-phase flow| US7178742B2|2003-05-06|2007-02-20|Lear Corporation|Fluid delivery system for spray applicator| SE526878C2|2003-06-18|2005-11-15|Q Med Ab|Medical pump| US7137572B2|2003-07-22|2006-11-21|Muh-Rong Wang|Metal atomizing device| ES2565232T3|2003-08-13|2016-04-01|Unilever N.V.|Household spraying device| WO2005016548A1|2003-08-13|2005-02-24|Unilever Plc|Nozzle for a spray device| US6981439B2|2003-08-22|2006-01-03|Hr Textron, Inc.|Redundant flow control for hydraulic actuator systems| US7131597B2|2003-09-09|2006-11-07|Scattergood John R|Atomization technique for producing fine particles| US7140560B2|2003-09-26|2006-11-28|Parker-Hannifin Corporation|Nozzle assembly with fuel tube deflector| US6884232B1|2003-10-31|2005-04-26|Baxter International Inc.|Laparoscopic spray device and method of use| US7201336B2|2003-12-30|2007-04-10|3M Innovative Properties Company|Liquid spray gun with non-circular horn air outlet passageways and apertures| ES2282933T3|2004-02-05|2007-10-16|Haldor Topsoe A/S|INJECTION NOZZLE AND METHOD FOR UNIFORMING INJECTION OF A FLUID CURRENT IN A HIGH TEMPERATURE GAS CURRENT THROUGH THE INJECTION NOZZLE.| US7275699B2|2004-05-06|2007-10-02|Thermal Science Technologies, Llc|Mobile pumping unit for dispensing insulating material in situ| DE102004030155B4|2004-06-22|2020-04-23|Robert Bosch Gmbh|Metering device and method for operating the same| US7178743B2|2004-06-29|2007-02-20|Clarke Consumer Products, Inc.|Portable sprayer| US7237693B2|2004-09-10|2007-07-03|Tah Industries, Inc.|Dual fluid cartridge for storing and dispensing fluids in unequal ratios| US7152813B2|2004-09-13|2006-12-26|Ding Hwa Co., Ltd.|Cap with a suction type spray head| US7225999B2|2004-09-23|2007-06-05|The United States Of America As Represented By The Secretary Of The Navy|Spray array apparatus| US7195180B2|2004-10-12|2007-03-27|The Boeing Company|Methods and systems for simulating multi-phase fluid flows, including fire suppressant flows| US7182279B2|2004-10-28|2007-02-27|National Cheng Kung University|Atomizer for atomizing molten metal| US7152396B2|2004-12-10|2006-12-26|General Motors Corporation|Reductant distributor for lean NOx trap| US7611494B2|2005-02-08|2009-11-03|Confluent Surgical, Inc.|Spray for fluent materials| US7140797B2|2005-02-18|2006-11-28|Plas-Pak Industries, Inc.|Multi-cartridge dispenser| US7237726B2|2005-03-29|2007-07-03|Pu Star Machinery Industrial Co., Ltd.|Paint sprayer gun| US7833216B2|2006-11-08|2010-11-16|Ethicon Endo-Surgery, Inc.|Fluid plunger adhesive dispenser| US20080272209A1|2007-02-09|2008-11-06|Terumo Kabushiki Kaisha|Sprayer| US8167172B2|2007-03-02|2012-05-01|Advanced Fluid Product Development, LLC|Compressed gas / carbon dioxide / hydraulic fluid dispenser| US20090131886A1|2007-11-16|2009-05-21|Liu Y King|Steerable vertebroplasty system| US8002753B2|2007-12-21|2011-08-23|Nordson Corporation|Self-contained pressurized injection device| US8033483B2|2008-04-25|2011-10-11|Confluent Surgical Inc.|Silicone spray tip| US20120000935A1|2010-06-30|2012-01-05|E. I. Du Pont De Nemours And Company|Self-contained hand held yoke-connected device for dispensng a two-part adhesive aerosol| GB2514853A|2013-06-08|2014-12-10|Keith Frederick Baylis|Sealant injection gun|
法律状态:
2017-03-02| DA2| Applications for amendment section 104|Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 06 FEB 2017 | 2017-05-25| DA3| Amendments made section 104|Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 06 FEB 2017 | 2017-06-15| FGA| Letters patent sealed or granted (standard patent)|
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申请号 | 申请日 | 专利标题 US201261681706P| true| 2012-08-10|2012-08-10|| US61/681,706||2012-08-10|| US13/922,640||2013-06-20|| US13/922,640|US10309430B2|2012-08-10|2013-06-20|Pneumatic actuation assembly| 相关专利
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